Technology Insights

COVID-19 research and innovation: 2021 open directory

Frances Wilkinson

Frances Wilkinson

Digital Content Officer

This ‘COVID-19 research and innovation 2021 open directory’ lists all the projects and opportunities we’ve received in response to our 2021 COVID-19 open call for research. Each of these projects has been submitted by an academic or research commercialisation professional with the aim of initiating meaningful conversations and partnerships leading to collaborative development and deployment of new pandemic interventions.

How to review the projects
A non-confidential summary of each project is hosted on IN-PART’s digital partnering platform for university-industry collaboration. Set up an account (it’s completely free), login, and follow the links below.

How to connect with the teams behind them
If you see a project that aligns with your R&D priorities, you can make a request for more information directly through the article on IN-PART. The academic team or project lead will then send you a response by email.

There are no costs or downstream fees for companies to use IN-PART’s matchmaking platform to connect with universities – it’s maintained by institutional subscriptions.

 

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COVID-19 research and innovation 2021 open directory

Content navigation:

  1. Diagnostics
  2. Drug Discovery
  3. Impacts on Society
  4. Medical Devices
  5. Modelling and Tracking
  6. PPE
  7. Research Tools
  8. Therapeutics
  9. Transmission Prevention and Control
  10. Vaccination

 

Diagnostics


Rapid and Ultrasensitive SARS-CoV-2 Antigen Detection for Acute COVID-19 Screening in Community Settings

University of Pennsylvania 
Read the project summary 

ORD Tech – Rapid Pathogen Testing
Oxford University Innovation
Read the project summary

Mass Antibody-Diagnosing Screen for COVID-19
University of Western Australia
Read the project summary

Antibody (IgG, IgA) Serology Test and Surrogate Neutralization Assay for SARS-CoV-2
Albert Einstein College of Medicine
Read the project summary

Novel Diagnostic Assay for the Detection of SARS-CoV-2 Variant Signatures
Innovate Calgary
Read the project summary 

Pooled Sample Testing Using Compressed Sensing for Increasing the Throughput and Reliability of Tests for the Detection of Defective Units in a Population
University of Iowa
Read the project summary 

Efficient Identification of Active Ingredients Against SARS-CoV-2 and Chemical Probes as Inhibitors of the 3CL and PL Proteases of Coronaviruses
TLB GmbH
Read the project summary 

ViralFx: Integrated Approach to the Diagnosis and Treatment of SARS-CoV-2
Sandia National Laboratories
Read the project summary 

Nucleocapsid protein for SARS-CoV-2 and other viruses
The University of Sheffield
Read the project summary 

SARS-CoV-2 Diagnostic Assay with Sensors of Immune Activation
The Ohio State University
Read the project summary (Added 24 MAY 2021)

Modified ACE2 (mACE2) – A High-Affinity Binder for SARS-CoV-2
Penn State University
Read the project summary (Added 16 JUNE 2021)

Rationally Designed SARS-CoV-2 Epitope-Scaffold Immunogens
Penn State University
Read the project summary (Added 16 JUNE 2021)

Cross-Neutralizing scFv Antibodies for COVID-19 Therapies
University of New Mexico
Read the project summary (Added 16 JUNE 2021)

Platform for Rapid Screening of Antibodies, Inhibitors and Vaccine Targets for Broad spectrum Activity Against all Future CoV2 Variants
University of Leicester
Read the project summary (Added 16 JUNE 2021)

A High-throughput Neutralization Test for SARS-CoV-2 Based on a Pseudovirus Containing Monomeric Infrared Fluorescent Protein as Reporter
University of Hawaii
Read the project summary (Added 16 JUNE 2021)

Colorimetric Aptasensor for the Rapid Diagnosis of SARS-CoV-2 (Covid-19)
University of the Western Cape
Read the project summary (Added 16 JUNE 2021)

Cognitive and Brain Function after COVID-19 Infection
Queen’s University 
Read the project summary (Added 16 JUNE 2021)

Treatment for Reducing Respiratory Distress in COVID-19 Patients
Queen’s University 
Read the project summary (Added 16 JUNE 2021)

Digital COVID-19 Testing with Machine Learning Analysis of Cough Sounds
Innovate Calgary 
Read the project summary (Added 16 JUNE 2021)

Digital and Point-of-Care Microfluidic Electrochemical Biosensor for Rapid, Longitudinal, Rapid, and Low-cost Detection of SARS-CoV-2 Viral Loads and Immunity Levels
Innovate Calgary 
Read the project summary (Added 16 JUNE 2021)

Point-of-Care Digital Droplet PCR
University of Notre Dame 
Read the project summary (Added 16 JUNE 2021)

Stabilised Pseudovirions for use as Positive Control in SARS-CoV-2 RNA Detection Kits
University of Cape Town 
Read the project summary (Added 21 JUNE 2021)

COVID-19 Diagnosis, Prognosis, and Treatment
Lawson Health Research Institute 
Read the project summary (Added 21 JUNE 2021)

COLOR: A Low-cost Optodiagnostic for Minute-time-scale Detection of SARS-CoV-2
University of Pennsylvania
Read the project summary (Added 21 JUNE 2021)

RAPID – A Low-cost Biosensor for Rapid Detection of SARS-CoV-2 at the Point-of-Care
University of Pennsylvania
Read the project summary (Added 21 JUNE 2021)

Serological Test for SARS-CoV-2
Emory University
Read the project summary (Added 28 JUNE 2021)

Use of Novel PLA-2 Inhibitors to Treat COVID-19 Infection and its Complications
Emory University
Read the project summary (Added 28 JUNE 2021)

Primary Human Nasal Epithelial Cells – Outsourced Testing or Supply of Experiment Ready Cells
Newcastle University
Read the project summary (Added 28 JUNE 2021)

 

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Drug Discovery


Anti-viral Nasal Spray

University of Birmingham
Read the project summary

Evaluating GPR4 as a Therapeutic Target for COVID-19
East Carolina University
Read the project summary

RNA-based Degrader Approach to Suppress Pan Viral Replication
Mount Sinai Health System
Read the project summary

Tools for the Study of SARS-CoV-2 in BSL-2 Laboratories
University of Iowa
Read the project summary

Computational Design of New and Optimized Therapeutical Binders for SARS-CoV-2
University of Sao Paulo
Read the project summary (Added 16 JUNE 2021)

Orally Available Small-Molecule Pan-antiviral (COVID-19, Influenza, RSV and Common Cold Coronavirus)
University of Nottingham
Read the project summary (Added 16 JUNE 2021)

A New Source of Native Human Targets in High Throughput Screening (HTS) of Enzyme Inhibitors – TMPRSS2 as a Target for Drug Development Against Coronaviruses
University of Antwerp
Read the project summary (Added 16 JUNE 2021)

Cellular Assays and New Product Development for COVID-19 Cytokine Storm
University of Huddersfield
Read the project summary (Added 16 JUNE 2021)

Stabilized Recombinant Spike Protein and SARS-CoV-2 Antibodies
La Jolla Institute for Immunology
Read the project summary (Added 21 JUNE 2021)

Genetically Encoded, Live Cell, BRET-based SARS-CoV-2 Mpro Protease Activity Sensor
Qatar Foundation
Read the project summary (Added 21 JUNE 2021)

 

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Impact on Society

 

Supporting Mental Health and Preventing Moral Injury Among Long-Term Care Workers
Innovate Calgary
Read the project summary (Added 16 JUNE 2021)

Neurobiological Correlates of Trauma-related Disorders and Stressors in Patients Who Have Suffered COVID-19
Polytechnic University of Catalonia
Read the project summary (Added 16 JUNE 2021)

 

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Medical Devices

 

Next Generation Nebuliser
University of Glasgow
Read the project summary (Added 16 JUNE 2021)

Valence InVent Xtend – An Innovative Solution to Safely Double or Triple Ventilator Capacity
Innovate Calgary
Read the project summary (Added 28 JUNE 2021)

 

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Modelling and Tracking


A Longitudinal Study Measuring COVID-19 Infection Status and the Level of Anti-SARS-CoV-2 Antibodies in Staff and Clinical Trial Volunteers

Richmond Research Institute
Read the project summary

DiRAP (Disease Risk Analysis App)
Innovate Calgary
Read the project summary (Added 16 JUNE 2021)

 

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PPE


Vacuum Face Mask to Limit Dispersion of Potentially Infectious Droplets

University of Utah
Read the project summary

Configurable Face Shield to Protect Against Viral Infection
University of Iowa
Read the project summary

Device for Ultraviolet Light Sterilization of Face Masks and Other Items
Florida Atlantic University
Read the project summary (Added 02 JUNE 2021)

Infection Control System for Resuscitation and Airway Management
Emory University
Read the project summary (Added 16 JUNE 2021)

Boosting Antiviral Capability of Face Masks
Innovate Calgary
Read the project summary (Added 16 JUNE 2021)

Synchronous UV-C Decontamination Chamber (SUDS) for Decontamination of N95 Masks.
Case Western Reserve University
Read the project summary (Added 28 JUNE 2021)

 

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Research Tools

 

Broad Spectrum Inhibitors of Coronavirus Active Against all Viral Variants
University of Leicester
Read the project summary (Added 16 JUNE 2021)

Pattern Alignment Clustering to Reveal Functionality in Biosequences – WeMineTM
University of Waterloo
Read the project summary (Added 16 JUNE 2021)

 

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 Transmission Prevention and Control

 

Investigating Environmental Stability and Developing Antiviral Products Against Human Coronavirus
De Montfort University Leicester
Read the project summary (Added 16 JUNE 2021)

Anti Covid-19 Stainless Steel
The University of Hong Kong
Read the project summary (Added 21 JUNE 2021)

Bus Passenger Occupation Forecasting with Deep Learning Methods
Polytechnic University of Catalonia
Read the project summary (Added 28 JUNE 2021)

Alert System and Decision Support for the Analysis of Containment and Response Options for Pandemic Situations
Polytechnic University of Catalonia
Read the project summary (Added 28 JUNE 2021)

 

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Therapeutics


Sub-20nM SARS CoV-2 Main Protease Non-covalent, Non-peptidic Remdesivir- Synergistic Inhibitors

Yale University
Read the project summary

Novel Inhibitors of SARS-CoV-2 PLpro
University of Arizona
Read the project summary 

A Broad-spectrum Antiviral for the Next Pandemic
Albert Einstein College of Medicine
Read the project summary

Early Therapeutic Interventions for CoViD-19 (Pharmacy Support Pack)
University of Huddersfield
Read the project summary

Broad-Spectrum Antiviral Materials
University of Manchester
Read the project summary (Added 24 MAY 2021)

Imaging and Novel Therapies for SARS-CoV-2 and Variants of Concern
Innovate Calgary
Read the project summary (Added 24 MAY 2021)

A Synthetic, Small Molecule for the Treatment of Enveloped Viruses like SARS-CoV-2
Virginia Commonwealth University
Read the project summary (Added 24 MAY 2021)

A Novel Therapeutic Platform for COVID-19
East Carolina University
Read the project summary (Added 24 MAY 2021)

Morus Alba Extract for Prevention and Treatment of COVID-19
University of Vienna
Read the project summary (Added 24 MAY 2021)

Treatment of Severe Covid19 Disease Using a Biological in Second Medical Use
Saarland University
Read the project summary (Added 24 MAY 2021)

PLpro Inhibitors Against SARS-CoV-2
University of Arizona
Read the project summary (Added 24 MAY 2021)

Novel Main Protease Inhibitors as SARS-CoV-2 Antivirals
University of Arizona
Read the project summary (Added 24 MAY 2021)

RIG-I RNA-based Immunotherapeutics
Oregon Health & Science University
Read the project summary (Added 02 JUNE 2021)

Dietary Supplement for COVID-19 Prevention and Treatment
North Carolina State University
Read the project summary (Added 16 JUNE 2021)

Covid-19 Anti-inflammatory Drugs
University of New Mexico
Read the project summary (Added 16 JUNE 2021)

Novel Hydroxyethylamine Based Synthetic Compound as Potent Therapeutic Targeting a RNA-Directed RNA Polymerase of SARS-CoV-2
University of New Mexico
Read the project summary (Added 16 JUNE 2021)

Broad Spectrum Inhibitors of Coronavirus Active Against all Viral Variants
University of Leicester
Read the project summary (Added 16 JUNE 2021)

Novel SARS-CoV-2 Therapeutic
University of British Columbia
Read the project summary (Added 16 JUNE 2021)

Type II Transmembrane Serine Protease Inhibitors as Host-based Broad Range Antivirals
Transfer Tech Sherbrooke
Read the project summary (Added 16 JUNE 2021)

Targeted Antibody Therapeutics
Sandia National Laboratory
Read the project summary (Added 16 JUNE 2021)

Therapeutics for Viral Induced Inflammatory Diseases Including COVID-19 Pneumonia
Seoul National University
Read the project summary (Added 21 JUNE 2021)

SARS-CoV-2 Neutralizing Human Monoclonal Antibodies
Emory University
Read the project summary (Added 21 JUNE 2021)

Stabilised RNA Therapeutics
Durham University
Read the project summary (Added 21 JUNE 2021)

Next-generation Anti-inflammatory Therapeutics for COVID-19 Pneumonia
Seoul National University
Read the project summary (Added 28 JUNE 2021)

Developing Neutralizing Antibodies to SARS-CoV-2 Envelope as Sustainable Therapeutics for COVID-19 and Future Cases
Columbia University
Read the project summary (Added 28 JUNE 2021)

TYK2 Antisense Oligonucleotides for Treatment of Severe COVID-19
Nanyang Technological University
Read the project summary (Added 28 JUNE 2021)

Monoclonal Antibodies for Inhibiting SARS-CoV-2 Infection of Host Human Cells
University of Salerno
Read the project summary (Added 28 JUNE 2021)

SARS-CoV-2 Neutralizing Monoclonal Antibodies and Therapeutic Application Thereof
Ghent University
Read the project summary (Added 28 JUNE 2021)

Using Long dsRNA to Block Coronavirus Replication via RNAi
Wilfrid Laurier University
Read the project summary (Added 28 JUNE 2021)

 

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Vaccination


Population-scale SARS-CoV-2 Vaccine

Children’s Hospital of Philadelphia
Read the project summary

COVID Vaccine Storage at Room Temperatures
The University of North Carolina at Charlotte
Read the project summary

Chimeric 3C-RBD Recombinant COVID-19 Vaccines to Enhance Cellular Immunity
NUI Galway 
Read the project summary (Added 16 JUNE 2021)

Improved T Cell Immunity Against SARS-CoV-2 – An Innovate Vaccine Strategy to Prevent Viral Infections
Lund University
Read the project summary (Added 16 JUNE 2021)

MVA Based SARS-CoV-2 Vaccines
Emory University
Read the project summary (Added 28 JUNE 2021)

 

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Additional COVID-19 research and innovation 2021 resources & content:

If you have any questions or want to speak with our team about our COVID-19 research and innovation directory, or any of the work we’re doing in response to COVID-19, feel free to send us a message at: alex@in-part.co.uk.

Copyrights reserved unless otherwise agreed – IN-PART Publishing Ltd., 2021: ‘COVID-19 research and innovation 2021 open directory

 


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